Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle
نویسندگان
چکیده
منابع مشابه
Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle: comparison to bovine spongiform encephalopathy in cattle.
Prion diseases or transmissible spongiform encephalopathies (TSEs) of animals include scrapie of sheep and goats; transmissible mink encephalopathy (TME); chronic wasting disease (CWD) of deer, elk and moose; and bovine spongiform encephalopathy (BSE) of cattle. The emergence of BSE and its spread to human beings in the form of variant Creutzfeldt-Jakob disease (vCJD) resulted in interest in su...
متن کاملTransmissible Spongiform Encephalopathies
Neuronal death represents the primary pathology of neurodegenerative diseases such as Alzheimer's and Parkinson’s disease and Amyotrophic Lateral Sclerosis. These diseases usually present with a slow onset and a chronic progression. Various regions of the brain, spinal cord, or peripheral nerves may be affected, leading to functional impairment and neuron loss. Neurodegenerative diseases are of...
متن کاملHuman Transmissible Spongiform Encephalopathies
Creutzfeldt-Jakob disease (CJD) is a rare and fatal human neurodegenerative condition characterized in most cases by a rapidly progressive dementia, myoclonus, and a periodic electroencephalogram (EEG). It is classified as a transmissible spongiform encephalopathy (TSE) because it causes characteristic spongy degeneration of the brain and can be transmitted to laboratory animals. TSEs also affe...
متن کاملTransmissible spongiform encephalopathies
Keywords Disease name and synonyms Included diseases Definition Pathogenesis Sporadic CJD Genetic forms of TSE Acquired forms of TSE Treatment Conclusion References Abstract Human prion diseases or transmissible spongiform encephalopathies (TSE) are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane prot...
متن کاملTransmissible spongiform encephalopathies.
Vet Med Today: Zoonosis Update 1705 T spongiform encephalopathies affect humans and other animals. Clinically, the diseases involve severe, progressive neurodegeneration with an invariably fatal outcome. The TSEs are linked by the unusual nature of their causative agent, which is believed to be a transmissible protein devoid of nucleic acid. This protein, known as a prion (a pseudoabbreviation ...
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ژورنال
عنوان ژورنال: Journal of Veterinary Diagnostic Investigation
سال: 2011
ISSN: 1040-6387,1943-4936
DOI: 10.1177/1040638711403404